Discovery of Novel Small Molecule Activators of β-Catenin Signaling

Wnt/β-catenin signaling plays a major role in embryonic development and adult stem cell maintenance. Reduced activation of the Wnt/β-catenin pathway underlies neurodegenerative disorders and aberrations in bone formation. Screening of a small molecule compound library with a β-galactosidase fragment...

Descripción completa

Detalles Bibliográficos
Autores principales: Verkaar, Folkert, van der Stelt, Mario, Blankesteijn, W. Matthijs, van der Doelen, Antoon A., Zaman, Guido J. R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084789/
https://www.ncbi.nlm.nih.gov/pubmed/21559429
http://dx.doi.org/10.1371/journal.pone.0019185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084789/
https://www.ncbi.nlm.nih.gov/pubmed/21559429
http://dx.doi.org/10.1371/journal.pone.0019185

Ejemplares similares