SPG20 Protein Spartin Associates with Cardiolipin via Its Plant-Related Senescence Domain and Regulates Mitochondrial Ca(2+) Homeostasis

Hereditary spastic paraplegias (HSPs) are a group of neurological disorders characterized clinically by spasticity of lower limbs and pathologically by degeneration of the corticospinal tract. Troyer syndrome is an autosomal recessive HSP caused by a frameshift mutation in the spartin (SPG20) gene....

Descripción completa

Detalles Bibliográficos
Autores principales: Joshi, Dinesh C., Bakowska, Joanna C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084803/
https://www.ncbi.nlm.nih.gov/pubmed/21559443
http://dx.doi.org/10.1371/journal.pone.0019290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084803/
https://www.ncbi.nlm.nih.gov/pubmed/21559443
http://dx.doi.org/10.1371/journal.pone.0019290

Ejemplares similares