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Modeling Initiation of Ewing Sarcoma in Human Neural Crest Cells

Ewing sarcoma family tumors (ESFT) are aggressive bone and soft tissue tumors that express EWS-ETS fusion genes as driver mutations. Although the histogenesis of ESFT is controversial, mesenchymal (MSC) and/or neural crest (NCSC) stem cells have been implicated as cells of origin. For the current st...

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Detalles Bibliográficos
Autores principales: von Levetzow, Cornelia, Jiang, Xiaohua, Gwye, Ynnez, von Levetzow, Gregor, Hung, Long, Cooper, Aaron, Hsu, Jessie Hao-Ru, Lawlor, Elizabeth R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084816/
https://www.ncbi.nlm.nih.gov/pubmed/21559395
http://dx.doi.org/10.1371/journal.pone.0019305