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Rac1 Deletion Causes Thymic Atrophy

The thymic stroma supports T lymphocyte development and consists of an epithelium maintained by thymic epithelial progenitors. The molecular pathways that govern epithelial homeostasis are poorly understood. Here we demonstrate that deletion of Rac1 in Keratin 5/Keratin 14 expressing embryonic and a...

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Detalles Bibliográficos
Autores principales: Hunziker, Lukas, Aznar Benitah, Salvador, Braun, Kristin M., Jensen, Kim, McNulty, Katrina, Butler, Colin, Potton, Elspeth, Nye, Emma, Boyd, Richard, Laurent, Geoff, Glogauer, Michael, Wright, Nick A., Watt, Fiona M., Janes, Sam M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084817/
https://www.ncbi.nlm.nih.gov/pubmed/21559396
http://dx.doi.org/10.1371/journal.pone.0019292