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Interaction of Bestrophin-1 and Ca(2+) Channel β-Subunits: Identification of New Binding Domains on the Bestrophin-1 C-Terminus
Bestrophin-1 modulates currents through voltage-dependent L-type Ca(2+) channels by physically interacting with the β-subunits of Ca(2+) channels. The main function of β-subunits is to regulate the number of pore-forming Ca(V)-subunits in the cell membrane and modulate Ca(2+) channel currents. To un...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084833/ https://www.ncbi.nlm.nih.gov/pubmed/21559412 http://dx.doi.org/10.1371/journal.pone.0019364 |