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Tyrosine 23 Phosphorylation-Dependent Cell-Surface Localization of Annexin A2 Is Required for Invasion and Metastases of Pancreatic Cancer

The aggressiveness of pancreatic ductal adenocarcinoma (PDA) is characterized by its high metastatic potential and lack of effective therapies, which is the result of a lack of understanding of the mechanisms involved in promoting PDA metastases. We identified Annexin A2 (ANXA2), a member of the Ann...

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Detalles Bibliográficos
Autores principales: Zheng, Lei, Foley, Kelly, Huang, Lanqing, Leubner, Ashley, Mo, Guanglan, Olino, Kelly, Edil, Barish H., Mizuma, Masamichi, Sharma, Rajni, Le, Dung T., Anders, Robert A., Illei, Peter B., Van Eyk, Jennifer E., Maitra, Anirban, Laheru, Daniel, Jaffee, Elizabeth M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084841/
https://www.ncbi.nlm.nih.gov/pubmed/21572519
http://dx.doi.org/10.1371/journal.pone.0019390