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Tyrosine 23 Phosphorylation-Dependent Cell-Surface Localization of Annexin A2 Is Required for Invasion and Metastases of Pancreatic Cancer
The aggressiveness of pancreatic ductal adenocarcinoma (PDA) is characterized by its high metastatic potential and lack of effective therapies, which is the result of a lack of understanding of the mechanisms involved in promoting PDA metastases. We identified Annexin A2 (ANXA2), a member of the Ann...
Autores principales: | Zheng, Lei, Foley, Kelly, Huang, Lanqing, Leubner, Ashley, Mo, Guanglan, Olino, Kelly, Edil, Barish H., Mizuma, Masamichi, Sharma, Rajni, Le, Dung T., Anders, Robert A., Illei, Peter B., Van Eyk, Jennifer E., Maitra, Anirban, Laheru, Daniel, Jaffee, Elizabeth M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084841/ https://www.ncbi.nlm.nih.gov/pubmed/21572519 http://dx.doi.org/10.1371/journal.pone.0019390 |
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