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Increased Right Ventricular Repolarization Gradients Promote Arrhythmogenesis in a Murine Model of Brugada Syndrome

Repolarization Gradients in Brugada Syndrome.Introduction: Brugada syndrome (BrS) is associated with loss of Na(+) channel function and increased risks of a ventricular tachycardia exacerbated by flecainide but reduced by quinidine. Previous studies in nongenetic models have implicated both altered...

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Detalles Bibliográficos
Autores principales: Martin, Claire A, Zhang, Yanmin, Grace, Andrew A, Huang, Christopher L-H
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Inc 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084998/
https://www.ncbi.nlm.nih.gov/pubmed/20384647
http://dx.doi.org/10.1111/j.1540-8167.2010.01767.x