HER2 status in gastro-oesophageal adenocarcinomas assessed by two rabbit monoclonal antibodies (SP3 and 4B5) and two in situ hybridization methods (FISH and SISH)

AIMS: HER2 gene amplification has been detected in 10–20% of gastric adenocarcinomas. In view of the recently demonstrated clinical benefit of the anti-human epidermal growth factor receptor 2 (HER2) drug trastuzumab in the treatment of advanced gastric cancer, reliable HER2 testing is of key import...

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Detalles Bibliográficos
Autores principales: Boers, James E, Meeuwissen, Harriëtte, Methorst, Natalie
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085073/
https://www.ncbi.nlm.nih.gov/pubmed/21323962
http://dx.doi.org/10.1111/j.1365-2559.2011.03760.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085073/
https://www.ncbi.nlm.nih.gov/pubmed/21323962
http://dx.doi.org/10.1111/j.1365-2559.2011.03760.x

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