Zinc-finger-based transcriptional repression of rhodopsin in a model of dominant retinitis pigmentosa

Despite the recent success of gene-based complementation approaches for genetic recessive traits, the development of therapeutic strategies for gain-of-function mutations poses great challenges. General therapeutic principles to correct these genetic defects mostly rely on post-transcriptional gene...

Descripción completa

Detalles Bibliográficos
Autores principales: Mussolino, Claudio, Sanges, Daniela, Marrocco, Elena, Bonetti, Ciro, Di Vicino, Umberto, Marigo, Valeria, Auricchio, Alberto, Meroni, Germana, Surace, Enrico Maria
Formato: Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2011
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085076/
https://www.ncbi.nlm.nih.gov/pubmed/21268285
http://dx.doi.org/10.1002/emmm.201000119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085076/
https://www.ncbi.nlm.nih.gov/pubmed/21268285
http://dx.doi.org/10.1002/emmm.201000119

Ejemplares similares