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Zinc-finger-based transcriptional repression of rhodopsin in a model of dominant retinitis pigmentosa

Despite the recent success of gene-based complementation approaches for genetic recessive traits, the development of therapeutic strategies for gain-of-function mutations poses great challenges. General therapeutic principles to correct these genetic defects mostly rely on post-transcriptional gene...

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Detalles Bibliográficos
Autores principales:	Mussolino, Claudio, Sanges, Daniela, Marrocco, Elena, Bonetti, Ciro, Di Vicino, Umberto, Marigo, Valeria, Auricchio, Alberto, Meroni, Germana, Surace, Enrico Maria
Formato:	Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2011
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085076/ https://www.ncbi.nlm.nih.gov/pubmed/21268285 http://dx.doi.org/10.1002/emmm.201000119

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