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Knockdown of NPM1 by RNA Interference Inhibits Cells Proliferation and Induces Apoptosis in Leukemic Cell Line

Nucleophosmin (NPM1) is an abundant and ubiquitously expressed phosphoprotein that is known to influence solid tumors progression. However, little is known about the role of NPM1 in leukemia. Here, we knocked down the NPM1 expression by RNA interference to investigate the role of NPM1 in leukemic ce...

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Detalles Bibliográficos
Autores principales: Qin, Feng-Xian, Shao, Hui-Yuan, Chen, Xian-Chun, Tan, Shi, Zhang, Hui-Juan, Miao, Zong-Yu, Wang, Li, Hui-Chen, Zhang, Ling
Formato: Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085175/
https://www.ncbi.nlm.nih.gov/pubmed/21537492