Synthesis and Evaluation of Amino Acid-Based Radiotracer (99m)Tc-N4-AMT for Breast Cancer Imaging

Purpose. This study was to develop an efficient synthesis of (99m)Tc-O-[3-(1,4,8,11-tetraazabicyclohexadecane)-propyl]-α-methyl tyrosine ((99m)Tc-N4-AMT) and evaluate its potential in cancer imaging. Methods. N4-AMT was synthesized by reacting N4-oxalate and 3-bromopropyl AMT (N-BOC, ethyl ester). I...

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Detalles Bibliográficos
Autores principales: Kong, Fan-Lin, Ali, Mohammad S., Zhang, Yinhan, Oh, Chang-Sok, Yu, Dong-Fang, Chanda, Mithu, Yang, David J.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085329/
https://www.ncbi.nlm.nih.gov/pubmed/21541217
http://dx.doi.org/10.1155/2011/276907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085329/
https://www.ncbi.nlm.nih.gov/pubmed/21541217
http://dx.doi.org/10.1155/2011/276907

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