Cargando…

A Novel Animal Model of Hippocampal Cognitive Deficits, Slow Neurodegeneration, and Neuroregeneration

Long-term adrenalectomy (ADX) results in an extensive and specific loss of dentate gyrus granule cells in the hippocampus of adult rats. This loss of granule cells extends over a period of weeks to months and ultimately results in cognitive deficits revealed in a number of tasks that depend on intac...

Descripción completa

Detalles Bibliográficos
Autores principales: Spanswick, Simon C., Lehmann, Hugo, Sutherland, Robert J.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085481/
https://www.ncbi.nlm.nih.gov/pubmed/21541187
http://dx.doi.org/10.1155/2011/527201