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Functions of MDMX in the Modulation of the p53-Response

The MDM family proteins MDM2 and MDMX are two critical regulators of the p53 tumor suppressor protein. Expression of both proteins is necessary for allowing the embryonal development by keeping the activity of p53 in check. Upon stresses that need to activate p53 to perform its function as guardian...

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Detalles Bibliográficos
Autores principales: Lenos, Kristiaan, Jochemsen, Aart G.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085504/
https://www.ncbi.nlm.nih.gov/pubmed/21541195
http://dx.doi.org/10.1155/2011/876173