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Methotrexate Toxicity in Growing Long Bones of Young Rats: A Model for Studying Cancer Chemotherapy-Induced Bone Growth Defects in Children

The advancement and intensive use of chemotherapy in treating childhood cancers has led to a growing population of young cancer survivors who face increased bone health risks. However, the underlying mechanisms for chemotherapy-induced skeletal defects remain largely unclear. Methotrexate (MTX), the...

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Detalles Bibliográficos
Autores principales: Fan, Chiaming, Georgiou, Kristen R., King, Tristan J., Xian, Cory J.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085506/
https://www.ncbi.nlm.nih.gov/pubmed/21541196
http://dx.doi.org/10.1155/2011/903097