Cargando…
Methotrexate Toxicity in Growing Long Bones of Young Rats: A Model for Studying Cancer Chemotherapy-Induced Bone Growth Defects in Children
The advancement and intensive use of chemotherapy in treating childhood cancers has led to a growing population of young cancer survivors who face increased bone health risks. However, the underlying mechanisms for chemotherapy-induced skeletal defects remain largely unclear. Methotrexate (MTX), the...
Autores principales: | Fan, Chiaming, Georgiou, Kristen R., King, Tristan J., Xian, Cory J. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085506/ https://www.ncbi.nlm.nih.gov/pubmed/21541196 http://dx.doi.org/10.1155/2011/903097 |
Ejemplares similares
-
Effects of Resveratrol Supplementation on Methotrexate Chemotherapy-Induced Bone Loss
por: Lee, Alice M. C., et al.
Publicado: (2017) -
Potential Effects of Phytoestrogen Genistein in Modulating Acute Methotrexate Chemotherapy-Induced Osteoclastogenesis and Bone Damage in Rats
por: King, Tristan J., et al.
Publicado: (2015) -
Prevention of Bone Growth Defects, Increased Bone Resorption and Marrow Adiposity with Folinic Acid in Rats Receiving Long-Term Methotrexate
por: Fan, Chia-Ming, et al.
Publicado: (2012) -
Notch2 Blockade Mitigates Methotrexate Chemotherapy-Induced Bone Loss and Marrow Adiposity
por: Peymanfar, Yaser, et al.
Publicado: (2022) -
Therapeutic Targeting Notch2 Protects Bone Micro-Vasculatures from Methotrexate Chemotherapy-Induced Adverse Effects in Rats
por: Peymanfar, Yaser, et al.
Publicado: (2022)