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Interferon Gamma Activated Macrophages Kill Mycobacteria by Nitric Oxide Induced Apoptosis

Mycobacterium tuberculosis is an intracellular pathogen of macrophages and escapes the macrophages' bactericidal effectors by interfering with phagosome-lysosome fusion. IFN-γ activation renders the macrophages capable of killing intracellular mycobacteria by overcoming the phagosome maturation...

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Detalles Bibliográficos
Autores principales: Herbst, Susanne, Schaible, Ulrich E., Schneider, Bianca E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085516/
https://www.ncbi.nlm.nih.gov/pubmed/21559306
http://dx.doi.org/10.1371/journal.pone.0019105