A New Strategy to Stabilize Oxytocin in Aqueous Solutions: I. The Effects of Divalent Metal Ions and Citrate Buffer

In the current study, the effect of metal ions in combination with buffers (citrate, acetate, pH 4.5) on the stability of aqueous solutions of oxytocin was investigated. Both monovalent metal ions (Na(+) and K(+)) and divalent metal ions (Ca(2+), Mg(2+), and Zn(2+)) were tested all as chloride salts...

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Detalles Bibliográficos
Autores principales: Avanti, Christina, Amorij, Jean-Pierre, Setyaningsih, Dewi, Hawe, Andrea, Jiskoot, Wim, Visser, Jan, Kedrov, Alexej, Driessen, Arnold J. M., Hinrichs, Wouter L. J., Frijlink, Henderik W.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085697/
https://www.ncbi.nlm.nih.gov/pubmed/21448747
http://dx.doi.org/10.1208/s12248-011-9268-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085697/
https://www.ncbi.nlm.nih.gov/pubmed/21448747
http://dx.doi.org/10.1208/s12248-011-9268-7

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