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Myocardial adaptation of energy metabolism to elevated preload depends on calcineurin activity: A proteomic approach

Chronic hemodynamic overload on the heart results in pathological myocardial hypertrophy, eventually followed by heart failure. Phosphatase calcineurin is a crucial mediator of this response. Little is known, however, about the role of calcineurin in response to acute alterations in loading conditio...

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Detalles Bibliográficos
Autores principales: Schott, Peter, Asif, Abdul R., Gräf, Christopher, Toischer, Karl, Hasenfuss, Gerd, Kögler, Harald
Formato: Texto
Lenguaje:English
Publicado: D. Steinkopff-Verlag 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085746/
https://www.ncbi.nlm.nih.gov/pubmed/18274801
http://dx.doi.org/10.1007/s00395-008-0696-1