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Myocardial adaptation of energy metabolism to elevated preload depends on calcineurin activity: A proteomic approach
Chronic hemodynamic overload on the heart results in pathological myocardial hypertrophy, eventually followed by heart failure. Phosphatase calcineurin is a crucial mediator of this response. Little is known, however, about the role of calcineurin in response to acute alterations in loading conditio...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
D. Steinkopff-Verlag
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085746/ https://www.ncbi.nlm.nih.gov/pubmed/18274801 http://dx.doi.org/10.1007/s00395-008-0696-1 |