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Mechanism of action of the new anti-ischemia drug ranolazine
Myocardial ischemia is associated with reduced ATP fluxes and decreased energy supply resulting in disturbances of intracellular ion homeostasis in cardiac myocytes. In the recent years, increased persistent (late) sodium current was suggested to contribute to disturbed ion homeostasis by elevating...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
D. Steinkopff-Verlag
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085780/ https://www.ncbi.nlm.nih.gov/pubmed/18046526 http://dx.doi.org/10.1007/s00392-007-0612-y |