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Urine Biomarkers of Risk in the Molecular Etiology of Breast Cancer

Endogenous estrogens can be bio-activated to endogenous carcinogens via formation of estrogen quinones. Estrogen-3,4-quinones react with DNA to form mutagenic depurinating estrogen-DNA adducts. The carcinogenicity of endogenous estrogens is related to unbalanced estrogen metabolism leading to excess...

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Detalles Bibliográficos
Autores principales: Gaikwad, Nilesh W., Yang, Li, Pruthi, Sandhya, Ingle, James N., Sandhu, Nicole, Rogan, Eleanor G., Cavalieri, Ercole L.
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086311/
https://www.ncbi.nlm.nih.gov/pubmed/21556245