Gastrointestinal toxicity of vorinostat: reanalysis of phase 1 study results with emphasis on dose-volume effects of pelvic radiotherapy

BACKGROUND: In early-phase studies with targeted therapeutics and radiotherapy, it may be difficult to decide whether an adverse event should be considered a dose-limiting toxicity (DLT) of the investigational systemic agent, as acute normal tissue toxicity is frequently encountered with radiation a...

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Detalles Bibliográficos
Autores principales: Bratland, Åse, Dueland, Svein, Hollywood, Donal, Flatmark, Kjersti, Ree, Anne H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086833/
https://www.ncbi.nlm.nih.gov/pubmed/21473790
http://dx.doi.org/10.1186/1748-717X-6-33

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086833/
https://www.ncbi.nlm.nih.gov/pubmed/21473790
http://dx.doi.org/10.1186/1748-717X-6-33

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