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An Adhesion-Dependent Switch between Mechanisms That Determine Motile Cell Shape
Keratocytes are fast-moving cells in which adhesion dynamics are tightly coupled to the actin polymerization motor that drives migration, resulting in highly coordinated cell movement. We have found that modifying the adhesive properties of the underlying substrate has a dramatic effect on keratocyt...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086868/ https://www.ncbi.nlm.nih.gov/pubmed/21559321 http://dx.doi.org/10.1371/journal.pbio.1001059 |