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Calpain Cleavage Prediction Using Multiple Kernel Learning

Calpain, an intracellular [Image: see text]-dependent cysteine protease, is known to play a role in a wide range of metabolic pathways through limited proteolysis of its substrates. However, only a limited number of these substrates are currently known, with the exact mechanism of substrate recognit...

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Detalles Bibliográficos
Autores principales: duVerle, David A., Ono, Yasuko, Sorimachi, Hiroyuki, Mamitsuka, Hiroshi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086883/
https://www.ncbi.nlm.nih.gov/pubmed/21559271
http://dx.doi.org/10.1371/journal.pone.0019035