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UMP/CMPK Is Not the Critical Enzyme in the Metabolism of Pyrimidine Ribonucleotide and Activation of Deoxycytidine Analogs in Human RKO Cells

BACKGROUND: Human UMP/CMP kinase was identified based on its enzymatic activity in vitro. The role of this protein is considered critical for the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells, based on the in vitro study of partially purified...

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Detalles Bibliográficos
Autores principales: Hu, Rong, Lam, Wing, Hsu, Chih-Hung, Cheng, Yung-Chi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086915/
https://www.ncbi.nlm.nih.gov/pubmed/21559290
http://dx.doi.org/10.1371/journal.pone.0019490