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UMP/CMPK Is Not the Critical Enzyme in the Metabolism of Pyrimidine Ribonucleotide and Activation of Deoxycytidine Analogs in Human RKO Cells
BACKGROUND: Human UMP/CMP kinase was identified based on its enzymatic activity in vitro. The role of this protein is considered critical for the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells, based on the in vitro study of partially purified...
Autores principales: | Hu, Rong, Lam, Wing, Hsu, Chih-Hung, Cheng, Yung-Chi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086915/ https://www.ncbi.nlm.nih.gov/pubmed/21559290 http://dx.doi.org/10.1371/journal.pone.0019490 |
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