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RBM4 down-regulates PTB and antagonizes its activity in muscle cell–specific alternative splicing
Alternative splicing contributes largely to cell differentiation and functional specification. We previously reported that the RNA-binding protein RBM4 antagonizes the activity of splicing factor PTB to modulate muscle cell–specific exon selection of α-tropomyosin. Here we show that down-regulation...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087008/ https://www.ncbi.nlm.nih.gov/pubmed/21518792 http://dx.doi.org/10.1083/jcb.201007131 |