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Hax1 regulates neutrophil adhesion and motility through RhoA

Kostmann disease is an inherited severe congenital neutropenia syndrome associated with loss-of-function mutations in an adaptor protein HS1-associated protein X-1 (Hax1). How Hax1 regulates neutrophil function remains largely unknown. In this paper, we use ribonucleic acid interference to deplete H...

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Detalles Bibliográficos
Autores principales: Cavnar, Peter J., Berthier, Erwin, Beebe, David J., Huttenlocher, Anna
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087009/
https://www.ncbi.nlm.nih.gov/pubmed/21518791
http://dx.doi.org/10.1083/jcb.201010143