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Role of phosphodiesterase and adenylate cyclase isozymes in murine colonic glucagon-like peptide 1 secreting cells

BACKGROUND AND PURPOSE: Glucagon-like peptide-1 (GLP-1) is secreted from enteroendocrine L-cells after food intake. Increasing GLP-1 signalling either through inhibition of the GLP-1 degrading enzyme dipeptidyl-peptidase IV or injection of GLP-1-mimetics has recently been successfully introduced for...

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Detalles Bibliográficos
Autores principales: Friedlander, Ronn S, Moss, Catherine E, Mace, Jessica, Parker, Helen E, Tolhurst, Gwen, Habib, Abdella M, Wachten, Sebastian, Cooper, Dermot M, Gribble, Fiona M, Reimann, Frank
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087130/
https://www.ncbi.nlm.nih.gov/pubmed/21054345
http://dx.doi.org/10.1111/j.1476-5381.2010.01107.x