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Tumour-specific HMG-CoAR is an independent predictor of recurrence free survival in epithelial ovarian cancer

BACKGROUND: Our group previously reported that tumour-specific expression of the rate-limiting enzyme in the mevalonate pathway, 3-hydroxy-3-methylglutharyl-coenzyme A reductase (HMG-CoAR) is associated with more favourable tumour parameters and a good prognosis in breast cancer. In the present stud...

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Detalles Bibliográficos
Autores principales: Brennan, Donal J, Brändstedt, Jenny, Rexhepaj, Elton, Foley, Michael, Pontén, Fredrik, Uhlén, Mathias, Gallagher, William M, O'Connor, Darran P, O'Herlihy, Colm, Jirstrom, Karin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087316/
https://www.ncbi.nlm.nih.gov/pubmed/20359358
http://dx.doi.org/10.1186/1471-2407-10-125