Considering scores between unrelated proteins in the search database improves profile comparison

BACKGROUND: Profile-based comparison of multiple sequence alignments is a powerful methodology for the detection remote protein sequence similarity, which is essential for the inference and analysis of protein structure, function, and evolution. Accurate estimation of statistical significance of det...

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Detalles Bibliográficos
Autores principales: Sadreyev, Ruslan I, Wang, Yong, Grishin, Nick V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087343/
https://www.ncbi.nlm.nih.gov/pubmed/19961610
http://dx.doi.org/10.1186/1471-2105-10-399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087343/
https://www.ncbi.nlm.nih.gov/pubmed/19961610
http://dx.doi.org/10.1186/1471-2105-10-399

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