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Considering scores between unrelated proteins in the search database improves profile comparison
BACKGROUND: Profile-based comparison of multiple sequence alignments is a powerful methodology for the detection remote protein sequence similarity, which is essential for the inference and analysis of protein structure, function, and evolution. Accurate estimation of statistical significance of det...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087343/ https://www.ncbi.nlm.nih.gov/pubmed/19961610 http://dx.doi.org/10.1186/1471-2105-10-399 |