Cargando…

Quantifying transduction efficiencies of unmodified and tyrosine capsid mutant AAV vectors in vitro using two ocular cell lines

PURPOSE: With the increasing number of retinal gene-based therapies and therapeutic constructs, in vitro bioassays characterizing vector transduction efficiency and quality are becoming increasingly important. Currently, in vitro assays quantifying vector transduction efficiency are performed predom...

Descripción completa

Detalles Bibliográficos
Autores principales: Ryals, Renee C., Boye, Sanford L., Dinculescu, Astra, Hauswirth, William W., Boye, Shannon E.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087449/
https://www.ncbi.nlm.nih.gov/pubmed/21552473