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Quantifying transduction efficiencies of unmodified and tyrosine capsid mutant AAV vectors in vitro using two ocular cell lines
PURPOSE: With the increasing number of retinal gene-based therapies and therapeutic constructs, in vitro bioassays characterizing vector transduction efficiency and quality are becoming increasingly important. Currently, in vitro assays quantifying vector transduction efficiency are performed predom...
Autores principales: | Ryals, Renee C., Boye, Sanford L., Dinculescu, Astra, Hauswirth, William W., Boye, Shannon E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087449/ https://www.ncbi.nlm.nih.gov/pubmed/21552473 |
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