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Quantifying transduction efficiencies of unmodified and tyrosine capsid mutant AAV vectors in vitro using two ocular cell lines

PURPOSE: With the increasing number of retinal gene-based therapies and therapeutic constructs, in vitro bioassays characterizing vector transduction efficiency and quality are becoming increasingly important. Currently, in vitro assays quantifying vector transduction efficiency are performed predom...

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Detalles Bibliográficos
Autores principales: Ryals, Renee C., Boye, Sanford L., Dinculescu, Astra, Hauswirth, William W., Boye, Shannon E.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087449/
https://www.ncbi.nlm.nih.gov/pubmed/21552473

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