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Degeneration of the mouse retina upon dysregulated activity of serum response factor

PURPOSE: Our aim was to generate and phenotypically characterize a transgenic mouse line expressing a constitutively active variant of the transcription regulatory protein serum response factor (SRF), namely the SRF-VP16 protein. This new mouse strain has been registered under the designation Gt(ROS...

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Detalles Bibliográficos
Autores principales: Sandström, Jenny, Heiduschka, Peter, Beck, Susanne C., Philippar, Ulrike, Seeliger, Matthias W., Schraermeyer, Ulrich, Nordheim, Alfred
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087454/
https://www.ncbi.nlm.nih.gov/pubmed/21552476