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Degeneration of the mouse retina upon dysregulated activity of serum response factor
PURPOSE: Our aim was to generate and phenotypically characterize a transgenic mouse line expressing a constitutively active variant of the transcription regulatory protein serum response factor (SRF), namely the SRF-VP16 protein. This new mouse strain has been registered under the designation Gt(ROS...
Autores principales: | Sandström, Jenny, Heiduschka, Peter, Beck, Susanne C., Philippar, Ulrike, Seeliger, Matthias W., Schraermeyer, Ulrich, Nordheim, Alfred |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087454/ https://www.ncbi.nlm.nih.gov/pubmed/21552476 |
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