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Evolution of the Kdo(2)-lipid A biosynthesis in bacteria

BACKGROUND: Lipid A is the highly immunoreactive endotoxic center of lipopolysaccharide (LPS). It anchors the LPS into the outer membrane of most Gram-negative bacteria. Lipid A can be recognized by animal cells, triggers defense-related responses, and causes Gram-negative sepsis. The biosynthesis o...

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Detalles Bibliográficos
Autores principales: Opiyo, Stephen O, Pardy, Rosevelt L, Moriyama, Hideaki, Moriyama, Etsuko N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087551/
https://www.ncbi.nlm.nih.gov/pubmed/21106097
http://dx.doi.org/10.1186/1471-2148-10-362