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Zinc-Chelation Contributes to the Anti-Angiogenic Effect of Ellagic Acid on Inhibiting MMP-2 Activity, Cell Migration and Tube Formation

BACKGROUND: Ellagic acid (EA), a dietary polyphenolic compound, has been demonstrated to exert anti-angiogenic effect but the detailed mechanism is not yet fully understood. The aim of this study was to investigate whether the zinc chelating activity of EA contributed to its anti-angiogenic effect....

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Detalles Bibliográficos
Autores principales: Huang, Sheng-Teng, Yang, Rong-Chi, Wu, Hsiao-Ting, Wang, Chao-Nin, Pang, Jong-Hwei S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087719/
https://www.ncbi.nlm.nih.gov/pubmed/21573219
http://dx.doi.org/10.1371/journal.pone.0018986