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Posttranslational Modification of 6-phosphofructo-1-kinase as an Important Feature of Cancer Metabolism

BACKGROUND: Human cancers consume larger amounts of glucose compared to normal tissues with most being converted and excreted as lactate despite abundant oxygen availability (Warburg effect). The underlying higher rate of glycolysis is therefore at the root of tumor formation and growth. Normal cont...

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Detalles Bibliográficos
Autores principales: Šmerc, Andreja, Sodja, Eva, Legiša, Matic
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087806/
https://www.ncbi.nlm.nih.gov/pubmed/21573193
http://dx.doi.org/10.1371/journal.pone.0019645