Munc13 Mediates the Transition from the Closed Syntaxin–Munc18 complex to the SNARE complex

During the priming step that leaves synaptic vesicles ready for neurotransmitter release, the SNARE syntaxin-1 transitions from a closed conformation that binds Munc18-1 tightly to an open conformation within the highly stable SNARE complex. Control of this conformational transition is key for brain...

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Detalles Bibliográficos
Autores principales: Ma, Cong, Li, Wei, Xu, Yibin, Rizo, Josep
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087822/
https://www.ncbi.nlm.nih.gov/pubmed/21499244
http://dx.doi.org/10.1038/nsmb.2047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087822/
https://www.ncbi.nlm.nih.gov/pubmed/21499244
http://dx.doi.org/10.1038/nsmb.2047

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