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A European survey on the detection and management of iron overload in transfusion-dependent patients with MDS
To better understand the detection and management of iron overload in transfusion-dependent patients with myelodysplastic syndromes (MDS), a 15-min web- or paper-based survey was conducted among 338 European physicians from 27 countries. Respondents had a mean of 18 years of clinical experience. For...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Springer-Verlag
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087870/ https://www.ncbi.nlm.nih.gov/pubmed/21327403 http://dx.doi.org/10.1007/s00277-011-1181-8 |
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author | Giagounidis, Aristoteles Leto di Priolo, Susanna Ille, Susanne Fenaux, Pierre |
author_facet | Giagounidis, Aristoteles Leto di Priolo, Susanna Ille, Susanne Fenaux, Pierre |
author_sort | Giagounidis, Aristoteles |
collection | PubMed |
description | To better understand the detection and management of iron overload in transfusion-dependent patients with myelodysplastic syndromes (MDS), a 15-min web- or paper-based survey was conducted among 338 European physicians from 27 countries. Respondents had a mean of 18 years of clinical experience. Forty-six percent and 27% of physicians noted that detecting and treating iron overload were either “very important” or “important,” respectively. The main reason for not actively exploring iron overload was related to poor patient prognosis, while the main reasons for not initiating iron chelation therapy were poor patient prognosis and older patient age. Thirty-seven percent and 31% of physicians believed that treating iron overload in these patients was “very important” or “important,” respectively. Ninety percent of physicians prescribed iron chelation therapy, and 38% of transfusion-dependent patients received iron chelation therapy. The key reasons for not initiating iron chelation therapy were related to poor patient prognosis (72%), patient age ≥85 years (50%), and comorbidities (34%). The views of these experienced MDS physicians reflect available international MDS treatment guidelines. |
format | Text |
id | pubmed-3087870 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Springer-Verlag |
record_format | MEDLINE/PubMed |
spelling | pubmed-30878702011-06-06 A European survey on the detection and management of iron overload in transfusion-dependent patients with MDS Giagounidis, Aristoteles Leto di Priolo, Susanna Ille, Susanne Fenaux, Pierre Ann Hematol Original Article To better understand the detection and management of iron overload in transfusion-dependent patients with myelodysplastic syndromes (MDS), a 15-min web- or paper-based survey was conducted among 338 European physicians from 27 countries. Respondents had a mean of 18 years of clinical experience. Forty-six percent and 27% of physicians noted that detecting and treating iron overload were either “very important” or “important,” respectively. The main reason for not actively exploring iron overload was related to poor patient prognosis, while the main reasons for not initiating iron chelation therapy were poor patient prognosis and older patient age. Thirty-seven percent and 31% of physicians believed that treating iron overload in these patients was “very important” or “important,” respectively. Ninety percent of physicians prescribed iron chelation therapy, and 38% of transfusion-dependent patients received iron chelation therapy. The key reasons for not initiating iron chelation therapy were related to poor patient prognosis (72%), patient age ≥85 years (50%), and comorbidities (34%). The views of these experienced MDS physicians reflect available international MDS treatment guidelines. Springer-Verlag 2011-02-16 2011 /pmc/articles/PMC3087870/ /pubmed/21327403 http://dx.doi.org/10.1007/s00277-011-1181-8 Text en © The Author(s) 2011 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. |
spellingShingle | Original Article Giagounidis, Aristoteles Leto di Priolo, Susanna Ille, Susanne Fenaux, Pierre A European survey on the detection and management of iron overload in transfusion-dependent patients with MDS |
title | A European survey on the detection and management of iron overload in transfusion-dependent patients with MDS |
title_full | A European survey on the detection and management of iron overload in transfusion-dependent patients with MDS |
title_fullStr | A European survey on the detection and management of iron overload in transfusion-dependent patients with MDS |
title_full_unstemmed | A European survey on the detection and management of iron overload in transfusion-dependent patients with MDS |
title_short | A European survey on the detection and management of iron overload in transfusion-dependent patients with MDS |
title_sort | european survey on the detection and management of iron overload in transfusion-dependent patients with mds |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087870/ https://www.ncbi.nlm.nih.gov/pubmed/21327403 http://dx.doi.org/10.1007/s00277-011-1181-8 |
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