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The Role of Mirk Kinase in Sarcomas

Targeting the tyrosine kinase KIT in gastrointestinal stromal tumors has led to improved treatment. Other kinases might serve as therapeutic targets in the more common forms of sarcoma. The kinase Mirk/dyrk1B is highly expressed in the vast majority of osteosarcomas and rhabdomyosarcomas and mediate...

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Detalles Bibliográficos
Autor principal: Friedman, Eileen
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087898/
https://www.ncbi.nlm.nih.gov/pubmed/21559261
http://dx.doi.org/10.1155/2011/260757