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Human Chondrosarcoma Cells Acquire an Epithelial-Like Gene Expression Pattern via an Epigenetic Switch: Evidence for Mesenchymal-Epithelial Transition during Sarcomagenesis

Chondrocytes are mesenchymally derived cells that reportedly acquire some epithelial characteristics; however, whether this is a progression through a mesenchymal to epithelial transition (MET) during chondrosarcoma development is still a matter of investigation. We observed that chondrosarcoma cell...

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Detalles Bibliográficos
Autores principales: Fitzgerald, Matthew P., Gourronc, Francoise, Teoh, Melissa L. T., Provenzano, Matthew J., Case, Adam J., Martin, James A., Domann, Frederick E.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087947/
https://www.ncbi.nlm.nih.gov/pubmed/21559267
http://dx.doi.org/10.1155/2011/598218