Cargando…
Advances in Molecular Characterization and Targeted Therapy in Dermatofibrosarcoma Protuberans
The molecular pathogenesis of dermatofibrosarcoma protuberans (DFSP) involves distinctive rearrangement of chromosomes 17 and 22 leading to formation of the COL1A1-PDGFB fusion gene. The knowledge of molecular events underlying development of DFSP resulted in the implementation of targeted therapy w...
Autores principales: | , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087969/ https://www.ncbi.nlm.nih.gov/pubmed/21559214 http://dx.doi.org/10.1155/2011/959132 |