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Advances in Molecular Characterization and Targeted Therapy in Dermatofibrosarcoma Protuberans

The molecular pathogenesis of dermatofibrosarcoma protuberans (DFSP) involves distinctive rearrangement of chromosomes 17 and 22 leading to formation of the COL1A1-PDGFB fusion gene. The knowledge of molecular events underlying development of DFSP resulted in the implementation of targeted therapy w...

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Detalles Bibliográficos
Autores principales: Rutkowski, Piotr, Wozniak, Agnieszka, Switaj, Tomasz
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087969/
https://www.ncbi.nlm.nih.gov/pubmed/21559214
http://dx.doi.org/10.1155/2011/959132