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Microscopic Analysis of Protein Oxidative Damage: Effect of Carbonylation on Structure, Dynamics, and Aggregability of Villin Headpiece

[Image: see text] One of the most important irreversible oxidative modifications of proteins is carbonylation, the process of introducing a carbonyl group in reaction with reactive oxygen species. Notably, carbonylation increases with the age of cells and is associated with the formation of intracel...

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Detalles Bibliográficos
Autores principales: Petrov, Drazen, Zagrovic, Bojan
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088313/
https://www.ncbi.nlm.nih.gov/pubmed/21506564
http://dx.doi.org/10.1021/ja110577e