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Bronchoalveolar CD4(+) T cell responses to respiratory antigens are impaired in HIV-infected adults

RATIONALE: HIV-infected adults are at an increased risk of lower respiratory tract infections. HIV infection impairs systemic acquired immunity, but there is limited information in humans on HIV-related cell-mediated immune defects in the lung. OBJECTIVE: To investigate antigen-specific CD4(+) T cel...

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Detalles Bibliográficos
Autores principales: Jambo, Kondwani C, Sepako, Enoch, Fullerton, Duncan G, Mzinza, David, Glennie, Sarah, Wright, Adam K, Heyderman, Robert S, Gordon, Stephen B
Formato: Texto
Lenguaje:English
Publicado: BMJ Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088469/
https://www.ncbi.nlm.nih.gov/pubmed/21357587
http://dx.doi.org/10.1136/thx.2010.153825