Compound C prevents Hypoxia-Inducible Factor-1α protein stabilization by regulating the cellular oxygen availability via interaction with Mitochondrial Complex I

The transcription factor Hypoxia-Inducible Factor-1α is a master regulator of the cellular response to low oxygen concentration. Compound C, an inhibitor of AMP-activated kinase, has been reported to inhibit hypoxia dependent Hypoxia-Inducible Factor-1α activation via a mechanism that is independent...

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Detalles Bibliográficos
Autores principales: Chua, Yee Liu, Hagen, Thilo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088540/
https://www.ncbi.nlm.nih.gov/pubmed/21481276
http://dx.doi.org/10.1186/1756-0500-4-117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088540/
https://www.ncbi.nlm.nih.gov/pubmed/21481276
http://dx.doi.org/10.1186/1756-0500-4-117

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