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Identification and Replication of Loci Involved in Camptothecin-Induced Cytotoxicity Using CEPH Pedigrees

To date, the Centre d'Etude Polymorphism Humain (CEPH) cell line model has only been used as a pharmacogenomic tool to evaluate which genes are responsible for the disparity in response to a single drug. The purpose of this study was demonstrate the model's ability to establish a specific...

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Detalles Bibliográficos
Autores principales: Watson, Venita Gresham, Motsinger-Reif, Alison, Hardison, Nicholas E., Peters, Eric J., Havener, Tammy M., Everitt, Lorraine, Auman, James Todd, Comins, Daniel L., McLeod, Howard L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088663/
https://www.ncbi.nlm.nih.gov/pubmed/21573211
http://dx.doi.org/10.1371/journal.pone.0017561