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Identification and Replication of Loci Involved in Camptothecin-Induced Cytotoxicity Using CEPH Pedigrees
To date, the Centre d'Etude Polymorphism Humain (CEPH) cell line model has only been used as a pharmacogenomic tool to evaluate which genes are responsible for the disparity in response to a single drug. The purpose of this study was demonstrate the model's ability to establish a specific...
Autores principales: | Watson, Venita Gresham, Motsinger-Reif, Alison, Hardison, Nicholas E., Peters, Eric J., Havener, Tammy M., Everitt, Lorraine, Auman, James Todd, Comins, Daniel L., McLeod, Howard L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088663/ https://www.ncbi.nlm.nih.gov/pubmed/21573211 http://dx.doi.org/10.1371/journal.pone.0017561 |
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